G303 Agronomy 716 Farm House Ln
(515) 294-2505 and (515) 708-3453
mbhattac@iastate.edu
G303 Agronomy 716 Farm House Ln
(515) 294-2505 and (515) 708-3453
mbhattac@iastate.edu
About
Bhattacharyya Lab is engaged in studying the molecular bases of two serious soybean diseases; the sudden death syndrome (SDS) and root and stem rot that are caused by Fusarium virguliforme and Phytophthora sojae, respectively. They have shown that FvTox1, a phytotoxin produced by F. virguliforme is involved in foliar SDS development. They then showed that by expressing an anti-FvTox1 plant antibody or FvTox1-interacting synthetic peptides one can enhance SDS resistance in soybean plants. They have mapped several quantitative trait loci governing SDS resistance and de novo sequenced F. virguliforme to identify pathogenicity genes involved in SDS development. They have shown that overexpression of two soybean genes, which are suppressed by F. virguliforme infection, enhances SDS resistance in transgenic soybean lines. One of these genes enhances resistance of soybean also against soybean aphids, spider mites and soybean cyst nematode. They have cloned the complex Rps1-k locus that governs the race-specific resistance of soybean against P. sojae pathotypes or races. There are two highly similar CC-NB-LRR-type genes in the Rps1-k locus that have been conferring Phytophthora resistance in soybean since 1980s. They have mapped several Rps genes including Rps1-k, Rps4, Rps6, Rps8, Rps12 and Rps13.
Bhattacharyya lab is also involved in understanding the nonhost resistance mechanisms of Arabidopsis against F. virguliforme and P. sojae. They identified 14 Arabidopsis mutants that are susceptible to both pathogens; and have cloned five genes that govern nonhost immunity of Arabidopsis against the two soybean pathogens. It appears that nonhost resistance mechanisms are highly complex and expression of these genes in transgenic soybean plants enhances SDS resistance.
Genetics and Genomics
Plant Biology
Bioinformatics and Computational Biology
Molecular, Cellular and Developmental Biology
Microbiology
People
2104B/1126H Agronomy, 716 Farm House Ln
(515) 294-3274
mwiedenh@iastate.edu
Publications
Publications
Sahoo, D.K., Hegde, C. and Bhattacharyya, M.K. (2023) Identification of multiple novel genetic mechanisms that regulate chilling tolerance in Arabidopsis. Frontiers in Plant Science 13:1094462. Published online 2023 Jan 12 doi: 10.3389/fpls.2022.1094462.
Wang, F., Das, P., Pal, N., Zhang, S. and Bhattacharyya, M.K. (2022) A phosphoproteomics study indicates involvement of type II metacaspases in the cell death pathway. Frontiers in Plant Science 13:882561. Published online 2022 Jul 19. doi: 10.3389/fpls.2022.882561
Li, S., Hanlon, R., Wise, H., Pal, N., Brar, H.K, Liao, C., Gao, H., Perez, E., Zhou, L.C., Tyler, B.M. and Bhattacharyya, M.K. (2021) Interaction of Phytophthora sojae effector Avr1b with E3 ubiquitin ligase GmPUB1 is required for recognition by soybeans carrying Phytophthora resistance Rps1-b and Rps1-k genes. Frontiers in Plant Science 12:725571. https://doi.org/10.3389/fpls.2021.725571
Sahoo, D.K., Das, A., Huang, X., Cianzio, S. and Bhattacharyya, M.K. (2021) Two tightly linked functional resistance genes provide broad-spectrum Phytophthora resistance in soybean. Scientific Reports. https://www.nature.com/articles/s41598-021-96425-1/metrics
Kambakam, S., Sahu, B.B., Ngaki, M.N., Kandel, D.R., Singh, P., Sumit, R., Swaminathan, S., Rajesh, M.K., and Bhattacharyya, M.K. (2021) Arabidopsis nonhost resistance PSS30 gene encoding a folate transporter enhances disease resistance in soybean. Plant J., https://doi.org/10.1111/tpj.15392
Zhou, H-K., Tang, K-Q., Li, G., Liu, W-Q., Yang, S-X., Bhattacharyya, M.K., Feng, X-Z. (2021) A robust and rapid candidate gene mapping pipeline based on M2 populations. Frontiers in Plant Science - Plant Breeding, 12:681816. doi: 10.3389/fpls.2021.681816
Geiser D. M., Al-Hatmi A., Aoki T., Arie T, Balmas V., Barnes I., Bergstrom G.C., Bhattacharyya M.K. et al. (2020) Phylogenomic analysis of a 55.1 kb 19-gene dataset resolves a monophyletic Fusarium that includes the Fusarium solani Species Complex. Phytopathology. 2020 Nov 17. https://doi.org/10.1094/PHYTO-08-20-0330-LE
Ngaki, M.N., Sahoo, D.K., Wang, B. and Bhattacharyya, M.K. (2020) Overexpression of a plasma membrane protein generated broad‐spectrum immunity in soybean. Plant Biotechnol. J. 19:502–516.
Cianzio, S.R., Arelli, P. R., Swaminathan, S., Bhattacharyya, M.K., Gebhart, G., Aboobucker, S. I., Carvalho, J. P. S. (2019). Registration of ‘IAR1902 SCN’ cultivar resistant to soybean cyst nematode and brown stem rot. J. Plant. Reg. 13:334–344.
Madhusudhan, P., Sinha, P., Rajput, L.S., Bhattacharyya, M., Sharma, T., Bhuvaneshwari, V., Gaikwad, K., Krishnan, S.G., and Singh, A.K. (2019) Effect of temperature on Pi54 mediated leaf blast resistance in rice. World J. Microbiol. Biotechnol. 35:148. doi:10.1007/s11274-019-2724-8.
Swaminathan, S., Das, A., Assefa, T., Knight, J.M., Ferreira Da Silva, A., Hartman, G.L., Huang, X., Cianzio, S. R., Bhattacharyya, M.K. (2019) Genome wide association study identifies novel single nucleotide polymorphic loci and candidate genes involved in soybean sudden death syndrome resistance. PLoS One 14(2):e0212071. doi: 10.1371/journal.pone.0212071. eCollection 2019.
Swaminathan, S., Abeysekara, N.S., Knight, J.M., Liu, M., Dong, J., Hudson, M.E., Bhattacharyya, M.K., and Cianzio, S.R. (2018). Mapping of new quantitative trait loci for sudden death syndrome and soybean cyst nematode resistance in two soybean population. Theor. Appl. Genet. 131:1047–1062.
Wang, B., Sumit, R., Sahu, B.B., Ngaki, M., Srivastava, S.K., Yang, Y., Swaminathan, S., and Bhattacharyya, M.K. (2018). An Arabidopsis glycine-rich plasma membrane protein enhances disease resistance in soybean. Plant Physiology 176:865-878.
Marshall, J., Qiao, X., Baumbach, J., Xie, J., Dong, L., Bhattacharyya, M.K. (2017) Microfluidic device enabled quantitative time-lapse microscopic-photography for phenotyping vegetative and reproductive phases in Fusarium virguliforme, which is pathogenic to soybean. Scientific Reports 7:44365.
Sahoo, D., Abeysekara, N., Cianzio, S., and Robertson, A.E., Bhattacharyya, M.K. (2017) A novel Phytophthora resistance gene, Rps12 mapped tightly to the Rps4/6 region in soybean. PLoS One, 12:e0169950.